Fermentation system

Applikon Pilot System 50L

Condition: used, This listing is for 1 of 2 Applikon BioPilot 70L Fermenter. The unit is in full working condition and is ready for immediate use Overview The Applikon BioPilot 70L is a fully integrated, pilot-scale fermentation system designed for microbial and cell culture applications in research, development, and small-scale production. Manufactured by Applikon Biotechnology, a global innovator in advanced bioreactor systems, the BioPilot 70L offers exceptional flexibility, process control, and scalability—bridging the gap between laboratory and production environments. Key Features Advanced Bioprocess Technology Precision Control: Integrated control of key parameters such as pH, dissolved oxygen (DO), temperature, agitation, and feed rates. Scalable Design: Built to mimic laboratory-scale conditions, enabling seamless scale-up to production volumes. Modular Automation: Compatible with Applikon ez-Control, DeltaV, or Lucullus® PIMS for sophisticated process control and data management. High-Quality Construction 70L Total Volume (50L Working Volume): Ideal for pilot studies, process optimization, and small-batch production. 316L Stainless Steel Vessel: Electro-polished and cGMP-compliant for pharmaceutical and biotechnological use. Jacketed Design: Enables precise temperature control via thermal fluid circulation. Technical Specifications Model: BioPilot 70L Total Volume: 70 liters Working Volume: 50 liters (typical) Vessel Material: 316L stainless steel, electro-polished Control Options: ez-Control, DeltaV, Lucullus® Sterilization: In-situ sterilizable (SIP) and Clean-in-Place (CIP) compatible Ports: Multiple ports for probes, additions, sampling, gas inlets/outlets Applications Biopharmaceuticals: Production of recombinant proteins, enzymes, vaccines Industrial Biotechnology: Fermentation of bio-based chemicals and specialty metabolites Food & Beverage: Cultivation of probiotics and functional ingredients Academic & R&D: Process development, scale-up studies, and microbial strain screening System Components Podpfjxhfngjx Adlepr 70L stainless steel fermentation vessel (jacketed) Modular control tower or integrated skid system Peristaltic pumps for acid/base, antifoam, and nutrient feed Autoclavable or SIP-compatible sensors for pH, DO, temperature, and level Gas flow control via mass flow controllers (MFCs) or rotameters Harvest and sampling ports, exhaust condenser, and sterile connections Quality Assurance Applikon fermentation systems are engineered and manufactured under strict quality control standards, ensuring full cGMP and FDA compliance where required. Factory Acceptance Testing (FAT), documentation, and validation support are provided for regulated environments. Benefits Flexible Configuration: Customizable to meet process-specific requirements Reliable Scale-Up: Accurate replication of lab-scale conditions in pilot volumes High-Level Automation: Advanced monitoring and control systems for optimized yields Ease of Integration: Compatible with existing bioprocess infrastructure Compliance-Ready: Suited for regulated production and research environments Conclusion The Applikon BioPilot 70L Fermentation System is the perfect solution for companies and institutions needing a reliable, scalable, and compliant bioreactor platform. With precise control, robust construction, and full integration capability, it empowers bioprocess development from the lab bench to commercial readiness.

Year of construction: 2022, condition: used, This listing is for the Cytiva AKTA Avant 150 Chromatography System The unit is in excellent condition with only around 2 years of use Cytiva AKTA Avant 150 Chromatography System is a bench-top preparative chromatography system primarily used for protein purification, method development, and process scale-up in research and biopharmaceutical settings. It belongs to Cytiva’s ÄKTA family of FPLC (Fast Protein Liquid Chromatography) instruments, designed for reproducible and automated biomolecule separation This instrument is ideal for: Ppsdeyk Erxjpfx Adlsr - Protein and antibody purification in research and early bioprocess stages. Bionex Scientific - Process development & method optimization prior to large-scale manufacture. Cytiva - Column packing and evaluation, especially for scale-up chromatography media. SelectScience - Biomolecule separation workflows in biotech, biochemistry, and analytical labs. Bionex Analytical

Condition: excellent (used), Used stainless steel container / transport container / IBC Last use: paint/lacquer Item number: 10710 Volume: 1000 liters Type: Vertical in galvanized stacking frame Height of feet: 100mm Material (wetted parts): 14301 / AISI 304 Manhole: Ø 400mm Design: Single-walled Operating pressure according to type plate: ATM Tank dimensions: Total height: 1670mm Pedpfsrdwyxjx Adlepr Total length: 1200mm Total width: 1100mm Materials: Interior: 14301 / AISI 304 External parts: Galvanized steel Equipment: Type plate: No Outlet diameter: 50mm Outlet valve: Ball valve Distance drain to floor: 220mm

Condition: used, This listing is for a Millipore Pro Flux M30 Tangential Flow Filtration (TFF) System. The unit is in full working condition and is ready for immediate release. The Millipore Pro Flux M30 is a high-performance tangential flow filtration (TFF) system designed for demanding applications in the biotechnology, pharmaceutical, and molecular diagnostics sectors. Optimized for crossflow filtration, the M30 provides reliable separation, concentration, and clarification of biomolecules and cell suspensions in both R&D and process-scale environments. With its robust stainless steel construction, precise transmembrane pressure (TMP) control, and compatibility with a wide range of membrane chemistries, the M30 delivers consistent performance across various filtration tasks—from protein concentration and virus clarification to cell culture harvest and synthetic biology sample prep. Key Features Stainless Steel Construction – Durable, sanitary design for aseptic operation and long-term reliability. Optimized TMP Control – Ensures maximum membrane efficiency and longevity through precise pressure regulation. Broad Membrane Compatibility – Supports a variety of membrane types and molecular weight cut-offs for flexible application use. Process Versatility – Suitable for concentration, diafiltration, and clarification steps in upstream and downstream workflows. Compact & Scalable – Ideal for laboratory-scale operations with scalability to pilot and production environments. User-Friendly Interface – Intuitive controls and gauges for straightforward operation and monitoring. Technical Specifications Model: Pro Flux M30 Flow Configuration: Tangential Flow / Crossflow Material of Construction: 316L Stainless Steel Pump Type: Peristaltic or Diaphragm (depending on setup) Pressure Control: Manual and/or automated transmembrane pressure regulation Operating Pressure Range: Typically up to 4 bar (60 psi) Filter Compatibility: Millipore Pellicon, Ultracel, Durapore, and other cassettes Tubing & Fittings: Sanitary-grade with tri-clamp or Luer lock connections Footprint: Compact benchtop design Manufacturer: Millipore (now part of Merck Millipore) Applications Biopharmaceutical Processing – Protein concentration, buffer exchange, and virus removal. Cell Culture Harvesting – Clarification of cell suspensions post-fermentation or bioreactor. Synthetic Biology – Preparation of cell-free extracts, nucleic acid concentration, and purification. Gene Editing & Molecular Cloning – Sample concentration and buffer exchange before downstream analysis. Diagnostics Manufacturing – Filtration of assay components and reagent prep for diagnostic kits. Fluorescence & Imaging Sample Prep – Ensures clean, debris-free samples for accurate analysis. Benefits Reliable Performance – Delivers consistent and reproducible results for critical bioprocess steps. Pedpfx Asxl Dx Sodlepr Process Flexibility – Adaptable to a wide range of biomolecule sizes and sample types. Aseptic Operation – Designed for cleanroom and GMP environments. Low Hold-Up Volume – Minimizes product loss during filtration. Trusted Brand – Developed by Millipore, a global leader in membrane filtration technologies.

Condition: used, This listing is for the Akta crossflow filtration system The unit is in full working condition and is ready for immediate use An ÄKTA Crossflow filtration system is a type of tangential flow filtration (TFF) system developed by Cytiva (formerly GE Healthcare). It's used primarily in bioprocessing and biotechnology applications to concentrate, diafilter, or clarify biological samples such as proteins, viruses, plasmids, and other biomolecule Core Functions: Concentration – Reducing the volume of a sample while retaining the target biomolecule. Diafiltration (Buffer Exchange) – Removing salts or changing the buffer environment by continuously adding a new buffer while removing permeate. Clarification – Removing particulates or cells from process fluids Key Components: Pump Modules: Typically peristaltic pumps that manage flow rates precisely. Filtration Cassettes: Hollow fiber or flat sheet membranes for ultrafiltration or microfiltration. Pressure Sensors: To monitor and control transmembrane pressure (TMP). Conductivity/pH/UV Detectors: For in-line monitoring of the filtrate and retentate. Benefits: Pedpexhf A Refx Adlspr Automation reduces operator error and variability. Scalable design for seamless transition from lab to production. Precise control of filtration parameters (flow rate, pressure, volume). CIP (Clean-In-Place) capabilities for easy maintenance and compliance with GMP. Common Applications: Protein concentration and buffer exchange Viral vector purification Plasmid DNA purification Cell harvest and clarification

Year of construction: 2018, condition: used, This listing is for a GE Healthcare UniFlux 120 Tangential Flow Filtration (TFF) System. The unit is in full working condition and ready for immediate release. The GE Healthcare UniFlux 120 is a fully automated Tangential Flow Filtration (TFF) system designed for clarification, concentration, and diafiltration applications in pilot to manufacturing-scale operations. With a flow rate range of 12 to 120 liters per minute, the UniFlux 120 is ideal for bioprocessing applications such as monoclonal antibody purification, vaccine production, and protein concentration. Ppedoxxx Inspfx Adlor Key Features & Benefits - Fully Automated Operation – The system is controlled by UNICORN software, ensuring seamless data logging, process automation, and compliance with regulatory standards - Versatile Filtration Options – Supports cassette or hollow fiber membranes. Conversion between formats is possible, with initial cassette holder installation requiring Cytiva Service. - High-Performance Filtration – Features a rotary lobe pump for precise flow control and optimized filtration efficiency. - Sanitary & GMP-Compliant Design – Constructed from stainless steel, making it suitable for pharmaceutical and biotechnology environments. - Scalability & Reliability – Designed to support process development and scale-up to commercial production, ensuring consistent filtration performance. Applications - Biopharmaceutical processing - Monoclonal antibody purification - Vaccine production - Protein concentration & buffer exchange - Cell culture clarification Technical Specifications - Flow Rate: 12 – 120 L/min - Pump Type: Rotary lobe pump - Filtration Format: Cassette & hollow fiber (conversion possible) - Control System: UNICORN software (FDA 21 CFR Part 11 compliant)