Used Sterilization for sale (184)

Condition: used, functionality: limited functionality, machine/vehicle number: Biocap DNA, Used Captair Biocap DNA UV sterilization cabinet Manufacturer: Captair / Erlab Model: BiocapDNA Voltage: 230V (50Hz) Hedpfx Ajxliivjg Njnu

Condition: excellent (used), Binder Type: Binder CB 210 CO² / 9140-0013 Technical data Temperature range 7 °C above room temperature to 60 °C MB1 controller for temperature and CO2 concentration Interior volume: 210 liters External dimensions (W x H x D): 740 x 1069 x 715 mm Internal dimensions (W x H x D): 560 x 750 x 500 mm Weight: approx. 121 kg Condition: used Scope of delivery: (see picture) (Changes and errors in the technical data, specifications are reserved!) Hedpfxjrp Enbs Ag Nonu We will be happy to answer any further questions you may have on the phone.

Condition: new, Year of construction: 2024, operating hours: 8 h, functionality: fully functional, machine/vehicle number: ONEYTA3PW8670900, overall weight: 650 kg, total length: 6,800 mm, total width: 850 mm, total height: 2,300 mm, input voltage: 380 V, type of input current: three-phase, input frequency: 50 Hz, power: 12 kW (16.32 HP), cable length: 1,500 mm, temperature: 300 °C, type of output current: three-phase, Custom made tea and herbs sterilization machine with Samsung magnetrons and electronic installed - ensemble by Nicole Technology The line is composed by two parts, main sterilization line and dosage machine. The capacity for sterilization of tea and herbs is 50kg/h. (Capacity may vary depend on the type of herbs). We can also provide our ISO 9001 standard operating procedure (SOP) for 15 different types of herbs. Installation of the equipment and putting the equipment into service can be provided. Spare parts - Two magnetrons Hnjdpfx Agsu H Urye Neu

Condition: used, This listing is for a Belimed PST 9-6-12 HS1 Steam Sterilizer. The unit is in excellent working condition and is ready for immediate release. Hnodpfoxmi Hqox Ag Nsu The Belimed PST 9-6-12 HS1 is a top-of-the-line pharmaceutical autoclave designed for saturated steam sterilization of laboratory and production equipment, including heat- and moisture-stable porous and non-porous loads. This advanced stainless steel sterilizer supports the 6050 and 6065 sterilization processes with integrated Filter Integrity System (FIS), ensuring reliable sterilization and validation compliance in regulated environments. Engineered by Belimed Life Science and manufactured in Germany, this system delivers high process reliability, precise temperature control, and full compliance with GMP/cGMP standards, making it ideal for use in research, pilot, and GMP production settings. This HS1 configuration features a single-door chamber, water-jacket cooling, vacuum-assisted drying, and a user-friendly B-Touch interface with integrated process control. It is optimized for efficient sterilization cycles with minimal operator intervention. Key Features GMP-ready design supporting pharmaceutical-grade sterilization processes (6050/6065) Integrated Filter Integrity System (FIS) for monitoring and verifying sterilization filter integrity User-friendly B-Touch touchscreen interface with Siemens WinCC Unified or Rockwell FT Optix Water-jacket cooling and vacuum drying ensure rapid cooling and effective drying of chamber loads Single-door HS1 configuration optimized for ergonomic loading and unloading High-quality AISI 316L stainless steel construction with hygienic surface finishes (Ra < 0.8 µm) Automated operation with redundant sensors and independent measurement circuits for reliable sterilization Compliance with GAMP5, 21 CFR Part 11, Annex 11, and optional ASME BPE certification Supports modular accessories including trolleys, batch carts, perforated or wire-mesh shelves, and cleanroom integration Technical Specifications Manufacturer: Belimed Life Science (Germany) Model: PST 9-6-12 HS1 Sterilization Processes: 6050 / 6065 (Steam, Pre-Vacuum, Gravity) Filter Integrity System (FIS): Yes Chamber Dimensions (W × D × H): 1030 × 600 × 1380 mm Usable Chamber Volume: 710–850 L External Dimensions (H × W × D): 1940 × 2150 × 1710 mm Weight: Approximately 1,010 kg Chamber Material: AISI 316L Stainless Steel Surface Finish: Ra < 0.8 µm (≤ 0.6 µm optional) Door Type: Single-door HS1 Loading Type: Ground loader (GR) Cooling System: Water-jacket cooling Vacuum System: Integrated water-ring vacuum pump with optional water recovery Control System: B-Touch interface with PLC Electrical Supply: 400 V / 50 Hz (other voltages optional) Compliance: GMP / cGMP, 21 CFR Part 11, Annex 11, ASME BPE options Year of Manufacture: Available on request Serial Number: Available on request Applications Sterilization of laboratory glassware, stainless steel equipment, and porous loads in biopharmaceutical production Small- to medium-scale pilot manufacturing with validated sterilization cycles GMP production environments requiring full regulatory compliance Sterilization of equipment used in vaccine, gene therapy, and biologics research Microbiology laboratories for culture media, instruments, and consumables Benefits Scalable and reliable for pilot and full production batches Validated sterilization with integrated FIS and redundant sensors ensures reproducible cycles High-...

Year of construction: 2020, condition: used, This listing is for a Pall UF/DF Tangential Flow Filtration System. The unit is in excellent working condition and is ready for immediate release. The Pall UF/DF System is a state-of-the-art tangential flow filtration (TFF) skid designed for ultrafiltration and diafiltration (UF/DF) processes in biopharmaceutical manufacturing. This advanced stainless steel unit enables efficient concentration and buffer exchange of biologics such as monoclonal antibodies, recombinant proteins, enzymes, and gene therapy vectors. Engineered by Pall Biotech and manufactured in Germany, this system ensures process reliability, hygiene, and scalability, meeting the rigorous demands of regulated production environments. Ideal for downstream processing in pilot or GMP production, this system features a user-friendly HMI interface, robust control panel, and a fully integrated filtration circuit compatible with single-use or reusable membranes. Key Features GMP-Ready Design – Engineered to support pharmaceutical-grade UF/DF processes. Integrated Touchscreen HMI – For real-time control and monitoring of process parameters. Compact Stainless Steel Skid – Easy to manoeuvre and install in classified cleanroom environments. Automated Operation – Equipped with an intelligent PLC for pressure, flow, and temperature control. Multi-Function System – Supports both ultrafiltration and diafiltration processes. High Purity Tubing & Fittings – Configured with sanitary connections and single-use flexibility. Validated Safety Features – Includes emergency stop button, regulated pressure alarms, and lockable panels. Hedpfx Agoxl D Awj Nonu Technical Specifications Parameter Details Manufacturer Pall Biotech (Germany) Year of Manufacture 2020 System Type UF/DF Skid (Ultrafiltration/Diafiltration) Max Allowable Pressure 4 bar (58 psi) Max Operating Temperature 80°C Min Operating Temperature 5°C Control System Touchscreen HMI with integrated PLC Construction 316L Stainless Steel Wheels Lockable castors for mobility CE Marking Yes (Compliant with EU standards) Serial Number Applications Biopharmaceutical Manufacturing – Concentration and buffer exchange for drug substances. Monoclonal Antibody Purification – Clarification and polishing prior to formulation. Gene Therapy & Vaccines – Processing of viral vectors, plasmid DNA, and mRNA. Enzyme and Protein Products – Downstream UF/DF concentration steps. Cell Culture Harvesting – Clarification of lysates and spent media. Formulation – Final buffer exchange before sterile filtration and fill/finish. Benefits Scalable Solution – Suitable for pilot-scale and full production batches. Reliable Filtration – Maintains membrane integrity and product quality. Process Efficiency – Fast changeover with user-friendly operation. High Product Recovery – Designed to minimize hold-up volume and product loss. Validated Platform – Developed by Pall, a global leader in bioprocessing technology.

Year of construction: 2014, condition: used, This listing is for a 3M Zeta Plus 16EZA Encapsulated System Holder The unit is in excellent working condition and is ready for immediate release. The 3M Encapsulated System Holder is engineered to support Zeta Plus depth filtration and related downstream purification processes with optimal ergonomics, hygiene, and operational efficiency. It is specifically designed for biopharmaceutical and biotechnology applications where sterile, high-throughput filtration is required. This system holder accommodates encapsulated filter capsules—eliminating the need for a stainless-steel housing—and offers a pivoting, ergonomic frame that enhances operator safety and eases filter change-outs. Key Features Pivoting Holder Design – The housing pivots between horizontal (waist-height) for loading/unloading and vertical for filtration mode, reducing operator strain and minimizing fluid spills during replacement. Vertical Flow Path Retained – Preserves the proven vertical flow design ideal for depth filtration with 3M Zeta Plus filters and compatibility with 3M polisher or chromatographic clarifiers. Torque-Limiter Sealing – Built-in torque limiter ensures the capsule shell is properly sealed before operation, protecting against leaks or misassembly. Encapsulated Shell Architecture – Eliminates the need for an external stainless-steel cartridge housing, thereby reducing facility clean‑in‑place (CIP) or validation overhead. Shell Options – Offers translucent polycarbonate shells for visual liquid level monitoring or polyphenylene oxide shells capable of sterilization and sanitization. Multiple Flow Configurations Supported – Enables Bottom-In / Bottom-Out and Top-In / Bottom-Out modes to optimize media usage and filter performance. Scalable Modules – Available in pilot and full-production configurations, facilitating scale‑up from lab to manufacturing scale within a unified system design. Technical Specifications Parameter Description Model / Part No. Housing 16EZA1 Flow Path Vertical flow design, compatible with multiple flow directions Shell Materials Polycarbonate or polyphenylene oxide options (sterilizable) Holder Orientation Pivoting between horizontal (load/unload) & vertical (operational) Hnsdpfx Agjxl Dy Nj Nsu Sealing Mechanism Torque‑limiter style sealing indicator Operational Scale Supports systems from small pilot scale up to production scale (0.5 L to >2,500 L) Filtration Compatibility 3M Zeta Plus depth filters, 3M Polisher ST, 3M Emphaze AEX Hybrid Purifier, 3M Harvest RC, etc. Footprint Compact vertical footprint; reduced spatial demand in filtration suites Applications Clarification of mammalian cell cultures prior to downstream purification Protection of downstream membranes and chromatography resins via depth filtration Clarification of bacterial, yeast, or insect cell lysates Removal of host cell proteins (HCP), DNA, endotoxins, and particulates Pre‑polishing or polishing after capture chromatography Viral clearance modes in downstream workflows Benefits & Value Proposition Enhanced Ergonomics & Safety – The pivoting design reduces the need to lift used capsules overhead, lowering risk of spills and operator fatigue. Lower Validation Burden – Because the system is fully encapsulated, no external housing cleaning or validation is needed in the customer’s site. Operational Versatility – Flexibility in shell types, flow configurations, and scale continuity from pilot to production. Visual Process Monitoring – Translucent shell...

Condition: used, This listing is for a Pall Allegro 50 L Standard Mixer and Weigh Platform. The unit is in full working condition and is ready for immediate release. The Pall Allegro 50 L Standard Mixer and Weigh Platform is a robust and versatile solution designed for single-use bioprocessing applications in the pharmaceutical and biotechnology industries. Engineered for consistent mixing performance, this system supports critical upstream and downstream operations including buffer preparation, media mixing, and formulation processes. This platform integrates high-precision weighing functionality with a reliable mixing system, offering enhanced process control in a compact, easy-to-clean stainless steel frame. Its compatibility with Pall Allegro single-use mixers ensures operational flexibility and sterility assurance across various applications. Key Features Integrated Design – Combines mixing and weighing in one streamlined system. Single-Use Compatible – Fully compatible with Pall Allegro 2D mixer bags. High Accuracy Weighing – Precision load cells for reliable mass control and batch documentation. User-Friendly Interface – Easy-to-use control panel with adjustable speed and mixing profiles. Hygienic Construction – Stainless steel frame with smooth surfaces for GMP compliance. Scalable Solution – Ideal for pilot-scale to small-scale commercial production. Technical Specifications Model: Allegro 50 L Standard Mixer & Weigh Platform Mixing Volume: Up to 50 liters Mixer Type: Magnetically driven impeller Platform Material: 304 Stainless Steel Weight Capacity: Up to 100 kg Dimensions (approx.): 600 mm x 600 mm x 1100 mm Power Supply: 100–240 V AC / 50–60 Hz Control System: Integrated touch screen interface Manufacturer: Pall Corporation Applications Biopharmaceutical Manufacturing – Media and buffer prep, formulation, and hold steps. Clinical Manufacturing – Flexible use in small-scale GMP operations. Vaccine Production – Sterile formulation and component mixing. Gene & Cell Therapy – Supports sterile, closed-system processing. Process Development Labs – Ideal for scaling up single-use technologies. Benefits Sterile Processing – Supports single-use bags to minimize contamination risk. Compact Footprint – Fits easily into lab and production environments. Accurate Dosing – Integrated weigh system for precise process control. Hnjdpfx Agsxl Dpde Nju Reduced Cleaning Time – No need for CIP/SIP due to disposable mixer bags. Pall Quality – Developed by a trusted leader in bioprocessing technologies.

Condition: used, This listing is for the Handilaz Mini Particle Counter complete with case and manual (Others available without case - see listings) The unit is in full working condition and is ready for immediate use Key Features Simultaneous Particle Counting: Sizes and counts particles in three fixed channels (0.3 µm, 0.5 µm, 5.0 µm) High Sensitivity: Detects particles from 0.2 µm to 10 µm, with resolution down to 10 nm Flow Rate: Consistent 0.1 CFM (2.83 L/min) with quiet pump and internal flow control Power Options: Can be powered via direct supply or portable with four high-capacity, quick-change, rechargeable NiMH AA batteries Data Management: Stores up to 10,000 samples Five distinct sampling modes CSV export via USB or SD card Data output through RS-232C or RS-485 Includes data download software Display & Interface: Touchscreen with one-button operation for ease of use Build Quality & Compliance: Diode laser light source ISO 21501-4 calibrated Includes IQ/OQ (Installation/Operation Qualification) documentation Extras: Compounding procedure templates provided Applications Cleanroom Certification: Hodexhga Dopfx Ag Nonu ISO 14644-1 certification and re-certification ISO classification for cleanrooms Routine Monitoring: Point-of-use particle measurements Ongoing cleanroom surveillance for compliance Contamination Troubleshooting: Locating local particle sources Verifying filter performance Filter & Leak Testing: Efficient detection of filter leaks and performance validation Compounding: Suitable for pharmaceutical or sterile compounding operations using pre-designed templates

Condition: used, This listing is for the Avestin EmulsiFlex-C5 for homogenizer with sealed toolings and spares The unit is in full working condition and is ready for immediate use EmulsiFlex-C5 High Pressure Homogenizer The Avestin EmulsiFlex-C5 is a high-pressure, pneumatically powered homogenizer designed for laboratory-scale applications. It is ideal for processing small to medium sample volumes, from 7 mL up to 5 L/h, depending on the pressure applied. How It Works: High Pressure Homogenisation High pressure homogenisation is an efficient and easy-to-use technique for cell disruption and liposome/emulsion processing. The principle involves pumping the sample through a valve with a small aperture. The sample transitions from very high pressure (up to 30,000 psi) on the pump side to atmospheric pressure on the outlet side. This sudden drop in pressure creates intense shear forces, disrupting cell membranes or dramatically reducing liposome/emulsion sizes. Hsdpfexhgawjx Ag Nonu For cells, the pressure-induced shear forces rupture the membranes, effectively lysing the cells. For liposomes and emulsions, this process reduces their size from micron to nanometer range, often resulting in uniform particles with narrow size distributions. Unique Features of the EmulsiFlex-C5 Dynamic Homogenising Valve The C5 uses a dynamic homogenising valve, which maintains constant pressure during sample processing. This consistency ensures the formation of highly uniform liposomes and micro-emulsions, with tight particle size distributions. Efficient Cell Disruption Most cells (including E. coli) can be lysed in a single pass, minimizing over-processing and reducing the risk of protein denaturation or degradation. Pressure Range: Adjustable from 500 to 30,000 psi Flow Rate: 1–5 L/h depending on pressure Minimum Sample Volume: 7 mL Holdback Volume: Less than 1 mL Temperature Control: Can be used with ice baths, external chillers, or in cold rooms Autoclavable: Easy cleaning and sterilization (SIP-compatible) Compact Size: 430 × 160 × 320 mm, 25 kg Power Source: Requires compressed or bottled air. For most applications (e.g., E. coli disruption or liposome formation), 100 psi air pressure is sufficient. Applications Disruption of bacterial, yeast, algal, insect, or mammalian cells Nano-sized liposome and emulsion formation Particle size reduction in pharmaceuticals, cosmetics, and food products Liposomal drug delivery systems Efficient homogenisation for biochemical and biophysical research

Condition: used, This listing is for 1 of 2 Handilaz Mini Particle Counter The unit is in full working condition and is ready for immediate use Key Features Simultaneous Particle Counting: Sizes and counts particles in three fixed channels (0.3 µm, 0.5 µm, 5.0 µm) High Sensitivity: Detects particles from 0.2 µm to 10 µm, with resolution down to 10 nm Flow Rate: Consistent 0.1 CFM (2.83 L/min) with quiet pump and internal flow control Power Options: Can be powered via direct supply or portable with four high-capacity, quick-change, rechargeable NiMH AA batteries Data Management: Stores up to 10,000 samples Five distinct sampling modes CSV export via USB or SD card Data output through RS-232C or RS-485 Includes data download software Display & Interface: Touchscreen with one-button operation for ease of use Build Quality & Compliance: Diode laser light source ISO 21501-4 calibrated Includes IQ/OQ (Installation/Operation Qualification) documentation Extras: Compounding procedure templates provided Hnsdsxhf Tispfx Ag Nju Applications Cleanroom Certification: ISO 14644-1 certification and re-certification ISO classification for cleanrooms Routine Monitoring: Point-of-use particle measurements Ongoing cleanroom surveillance for compliance Contamination Troubleshooting: Locating local particle sources Verifying filter performance Filter & Leak Testing: Efficient detection of filter leaks and performance validation Compounding: Suitable for pharmaceutical or sterile compounding operations using pre-designed templates

Condition: used, This listing is for the Binder BF115 Incubator The unit is in full working condition and is ready for immediate use BINDER BF 115 – e Series Forced Convection Incubator The BINDER BF 115 incubator from the e series is designed for precise and gentle incubation applications in laboratories where performance, uniformity, and reliability are critical. Work particularly well under a full load and large batch throughputs. This incubator is extremely homogeneous and has quick recovery time. Key Performance Features Temperature Range: Ambient +8 °C to 100 °C – ideal for a wide variety of microbiological, bacteriological, and stability testing. Excellent Uniformity & Stability: ±0.3 K uniformity at 37 °C ±0.1 K fluctuation at 37 °C ±1.6 K uniformity at 100 °C Fast Heating & Recovery: Heats to 37 °C in ~8 minutes Recovers in ~3 minutes after a 30-second door opening Design & Control Highlights e™ Technology: Ensures uniform temperature distribution across all shelves – even with full chamber loads. Forced Air Convection: Enables efficient heat transfer and consistent conditions throughout the chamber. Disinfection Routine: Built-in 100 °C sterilization cycle for internal decontamination. User Interface: Intuitive LCD controller with programmable timer, USB port for data logging, and electromechanical exhaust flap control. Safety Thermostat: Class 3.1 safety (DIN 12880 compliant) with visual alarm for over-temperature protection. Internal Viewing: Transparent inner glass door allows sample observation without disturbing internal environment. Technical Specifications Feature Details Chamber Volume 114 liters Temperature Range Ambient +8 °C to 100 °C Internal Dimensions 550 × 550 × 380 mm (W×H×D) Hsdpfxsxhfz Tj Ag Njnu External Dimensions 710 × 725 × 605 mm (W×H×D) Power Supply 230 V, 0.4 kW, 6.3 A fuse (also available in 120 V) Noise Level 43 dB(A) typical Weight ~54 kg Shelves 2 chrome-plated shelves (up to 5 possible) Energy Consumption ~60 Wh/h @ 37 °C; ~235 Wh/h @ 100 °C Applications & Benefits Use Cases: Ideal for microbiology, bacteriology, tissue culture, stability testing, and pharmaceutical incubation. Scalable Performance: Optimized for full load conditions and large batch throughput without compromising performance. User-Friendly: Stackable, ergonomic handle design, easy-to-clean stainless steel chamber with no fixed fixtures. Highly Reliable: Rapid recovery and precise temperature regulation for reproducible results, even with frequent door openings.

Condition: used, This listing is for the Binder BF115 UL Incubator / Oven The unit is in full working condition and is ready for immediate use BINDER BF 115 UL – Forced Convection Incubator The BINDER BF 115 incubator from the e series is designed for precise and gentle incubation applications in laboratories where performance, uniformity, and reliability are critical. Work particularly well under a full load and large batch throughputs. This incubator is extremely homogeneous and has quick recovery time. Key Performance Features Temperature Range: Ambient +8 °C to 100 °C – ideal for a wide variety of microbiological, bacteriological, and stability testing. Excellent Uniformity & Stability: ±0.3 K uniformity at 37 °C ±0.1 K fluctuation at 37 °C ±1.6 K uniformity at 100 °C Fast Heating & Recovery: Heats to 37 °C in ~8 minutes Recovers in ~3 minutes after a 30-second door opening Design & Control Highlights e™ Technology: Ensures uniform temperature distribution across all shelves – even with full chamber loads. Forced Air Convection: Enables efficient heat transfer and consistent conditions throughout the chamber. Disinfection Routine: Built-in 100 °C sterilization cycle for internal decontamination. User Interface: Intuitive LCD controller with programmable timer, USB port for data logging, and electromechanical exhaust flap control. Hsdexhfz Hopfx Ag Njnu Safety Thermostat: Class 3.1 safety (DIN 12880 compliant) with visual alarm for over-temperature protection. Internal Viewing: Transparent inner glass door allows sample observation without disturbing internal environment. Technical Specifications Feature Details Chamber Volume 114 liters Temperature Range Ambient +8 °C to 100 °C Power Supply 120 V, 12.5 A fuse (NB At this time we also have in stock 230 V See BF115) Noise Level 43 dB(A) typical Weight ~54 kg Shelves 2 chrome-plated shelves (up to 5 possible) Applications & Benefits Use Cases: Ideal for microbiology, bacteriology, tissue culture, stability testing, and pharmaceutical incubation. Scalable Performance: Optimized for full load conditions and large batch throughput without compromising performance. User-Friendly: Stackable, ergonomic handle design, easy-to-clean stainless steel chamber with no fixed fixtures. Highly Reliable: Rapid recovery and precise temperature regulation for reproducible results, even with frequent door openings.

Condition: used, This listing is for the Walker Class 11 Biological Safety Cabinet The unit is in full working condition and is ready for immediate use A Walker Biological Safety Cabinet is a type of biosafety cabinet (BSC) designed and manufactured by Walker, a company that specializes in laboratory containment equipment. These cabinets are used in laboratories to provide a controlled, contaminant-free environment for handling potentially hazardous biological materials. What Is a Biological Safety Cabinet? A Biological Safety Cabinet (BSC) is an enclosed, ventilated laboratory workspace designed to: Protect the user from exposure to biohazards, Protect the experiment or product from contamination, Prevent environmental contamination. They achieve this through HEPA (High-Efficiency Particulate Air) filtration and controlled airflow systems. Walker Biological Safety Cabinet – Key Features Hjdpfxsxhfr Es Ag Nsnu HEPA-filtered airflow: Removes airborne particles and microorganisms. Laminar airflow: Provides a clean work area by maintaining unidirectional air movement. Front access sash: Allows operator access while maintaining airflow barrier. UV light for sterilization when not in use. Ergonomic design: For user comfort during long procedures.

Condition: used, This listing is for 1 of 2 Quattro Fluid SystemFlow 1000S These units is in full working condition and is ready for immediate use Overview & Application The Quattroflow 1000 S is a quaternary (four‑piston) diaphragm positive‑displacement pump—engineered for gentle, sterile handling of shear‑sensitive fluids such as proteins, vaccines, cell suspensions, and other biopharmaceutical or food-grade products. Its design features—like seal‑less operation, low shear, low pulsation, and dry‑run capability—make it ideal for critical applications including: Filtration systems: Tangential‑flow filtration (TFF), recirculation pumps, filter cartridges Chromatography: Gradient mixing and feed pumps Centrifuge feeding and homogenization Aseptic filling lines and other sensitive processing tasks Commonly processed media include albumin, IgG antibodies, enzymes, vaccines, cell and virus suspensions, dairy products, and cosmetic or polymeric solutions. Technical Specifications Hnsdpfxjxhfp Re Ag Neu Here’s what’s known about its performance and build: Flow rate: Continuously variable between ~25 to 1000 L/h (at atmospheric pressure); around 750 L/h at 6 bar (depending on configuration) Max Pressure: Up to 6 bar, with high‑pressure variants available upon request Drive mechanism: Four‑piston diaphragm setup actuated by an eccentric shaft; standard variant uses a 5° eccentric shaft reaching up to 1,800 rpm Material & Construction: Pump head: Stainless steel grades 1.4435 or 1.4539, optional alternatives (like PEEK) available Membranes: Santoprene (diaphragm), EPDM (valve membranes) Priming and Pumping Features: Self‑priming, dry‑run capable Four directional porting—pump orientation flexible No shaft seals or wetted rotating parts, minimizing wear and product heating Internal volume (filling volume): Approx 35 mL; designed to minimize dead volume and aid product recovery Connections: Standard ¾″ TC (Tri‑Clamp) sanitary ferrule; other flange types available Dimensions & Weight: Pump: 523 × 155 × 212 mm, ~23 kg Control unit (frequency inverter): 350 × 155 × 212 mm, ~6 kg Electrical: 230 V AC (50 Hz) via a control box with 6.3 A fuse; motor IP54, control box IP53 Key Advantages This model offers several standout benefits: Gentle, high‑integrity fluid handling—ideal for fragile biologics due to low shear and pulsation Contamination-free design—no mechanical seals, minimal abrasion Robust operation—powerful 370 W motor, simplified maintenance with fewer parts Aseptic and sterile process readiness—autoclavable, self‑draining, hygienic construction Installation adaptability—four flow directions, small footprint, flexible hookups

Condition: used, This listing is for the ICN Biomedicals Flow Gelaire BSB Class 2 Safety Cabinet The unit is in full working condition and is ready for immediate use Gelaire Class II Biological Safety Cabinets These are widely used internationally and are known for their high safety, energy efficiency, and ergonomic design. Key features include: Airflow & Protection They employ part-recirculating laminar airflow and separate H14 HEPA systems for both supply and exhaust. The design ensures a consistent air barrier at the front opening and maintains sterile downflow inside, all within a biodynamic sealing system that uses negative pressure around any positive-pressure zones. Eco® Control System A smart microprocessor actively regulates airflow to compensate for filter loading, manage power consumption, and maintain safe operational flow rates. Monitoring & Safety Alarms Cabinets offer real-time display of airflow velocities, internal and external temperatures, operation hours, filter life, and fan power factor. Audible and visual alerts warn of airflow deviations or other malfunctions. Standby power-saving modes and “blackout” reporting (in the event of power failure) are included. Construction & Ergonomics The housing features antimicrobial powder-coat finish, and interior zones are stainless steel (Type 304 for work zones, Type 316 for the tray). Hinged or electric sash options (depending on model) and ISO-aligned ergonomic design, noise under 60 dB(A), and smooth operation are standard. Hodpfxexhfpqo Ag Nonu Options & Accessories Available extras include gas and vacuum taps, splashproof power outlets, UV germicidal lamps, different exhaust configurations (top, left, right), adjustable stands, carbon exhaust filters, armrests, and fumigation seals.

Condition: used, This listing is for 1 of 2 Applikon BioPilot 70L Fermenter. The unit is in full working condition and is ready for immediate use Overview The Applikon BioPilot 70L is a fully integrated, pilot-scale fermentation system designed for microbial and cell culture applications in research, development, and small-scale production. Manufactured by Applikon Biotechnology, a global innovator in advanced bioreactor systems, the BioPilot 70L offers exceptional flexibility, process control, and scalability—bridging the gap between laboratory and production environments. Key Features Advanced Bioprocess Technology Precision Control: Integrated control of key parameters such as pH, dissolved oxygen (DO), temperature, agitation, and feed rates. Scalable Design: Built to mimic laboratory-scale conditions, enabling seamless scale-up to production volumes. Modular Automation: Compatible with Applikon ez-Control, DeltaV, or Lucullus® PIMS for sophisticated process control and data management. High-Quality Construction 70L Total Volume (50L Working Volume): Ideal for pilot studies, process optimization, and small-batch production. 316L Stainless Steel Vessel: Electro-polished and cGMP-compliant for pharmaceutical and biotechnological use. Jacketed Design: Enables precise temperature control via thermal fluid circulation. Technical Specifications Model: BioPilot 70L Total Volume: 70 liters Working Volume: 50 liters (typical) Vessel Material: 316L stainless steel, electro-polished Control Options: ez-Control, DeltaV, Lucullus® Sterilization: In-situ sterilizable (SIP) and Clean-in-Place (CIP) compatible Ports: Multiple ports for probes, additions, sampling, gas inlets/outlets Applications Biopharmaceuticals: Production of recombinant proteins, enzymes, vaccines Industrial Biotechnology: Fermentation of bio-based chemicals and specialty metabolites Food & Beverage: Cultivation of probiotics and functional ingredients Hnsdpjxhfngjfx Ag Neu Academic & R&D: Process development, scale-up studies, and microbial strain screening System Components 70L stainless steel fermentation vessel (jacketed) Modular control tower or integrated skid system Peristaltic pumps for acid/base, antifoam, and nutrient feed Autoclavable or SIP-compatible sensors for pH, DO, temperature, and level Gas flow control via mass flow controllers (MFCs) or rotameters Harvest and sampling ports, exhaust condenser, and sterile connections Quality Assurance Applikon fermentation systems are engineered and manufactured under strict quality control standards, ensuring full cGMP and FDA compliance where required. Factory Acceptance Testing (FAT), documentation, and validation support are provided for regulated environments. Benefits Flexible Configuration: Customizable to meet process-specific requirements Reliable Scale-Up: Accurate replication of lab-scale conditions in pilot volumes High-Level Automation: Advanced monitoring and control systems for optimized yields Ease of Integration: Compatible with existing bioprocess infrastructure Compliance-Ready: Suited for regulated production and research environments Conclusion The Applikon BioPilot 70L Fermentation System is the perfect solution for companies and institutions needing a reliable, scalable, and compliant bioreactor platform. With precise control, robust construction, and full integration capability, it empowers bioprocess development from the lab bench to commercial readiness.

Year of construction: 2020, condition: used, This listing is for the Steris Reliance 380PG Washer/Disinfector. The unit is in full working condition and is ready for immediate use. Overview The Steris Reliance 380PG is a high-capacity washer/disinfector engineered for efficient cleaning and thermal disinfection of surgical instruments, utensils, and glassware. Manufactured by Steris, a global leader in infection prevention technologies, the 380PG combines robust construction, user-friendly automation, and advanced process control—making it ideal for central sterile services departments (CSSDs), laboratories, and pharmaceutical environments. Key Features Advanced Cleaning Technology Dual-Chamber Rack Design: Optimizes loading capacity and reduces cycle times for high-throughput operations. Programmable Microprocessor Control: Offers flexible cycle configuration with up to 50 user-defined programs. Thermal Disinfection: Achieves validated disinfection through controlled high-temperature rinse phases. Built for Demanding Use Stainless Steel Construction: Corrosion-resistant, durable 316L and 304 stainless steel ensures long-term reliability and hygiene. Double-Insulated Glass Doors: Provide thermal insulation and visual access to the chamber. Compact Footprint: Designed to maximize performance while minimizing floor space. Technical Specifications Model: Reliance 380PG Type: Washer/Disinfector Chamber Size: 10 DIN baskets (approximate) Control System: Microprocessor with digital HMI interface Cycle Capacity: Up to 120 DIN trays per 8-hour shift Construction: 316L stainless steel chamber, 304 stainless steel exterior Thermal Disinfection Temp: Up to 93°C (200°F) Applications Healthcare Facilities: Sterile processing of surgical instruments, containers, and reusable devices Pharmaceutical & Biotech: Cleaning of lab glassware, components, and production utensils Laboratory Settings: High-volume cleaning and disinfection of equipment and tools Research Institutions: Safe processing of experimental apparatus and reusable lab ware System Components Dual-compartment wash chamber with rotating spray arms Built-in dosing pumps for detergents and disinfectants User-friendly touchscreen control panel HEPA-filtered drying system Reversible hinged doors for pass-through or single-door configurations Quality Assurance Each unit is built and factory-tested under rigorous quality control standards to ensure compliance with EN ISO 15883 guidelines for washer-disinfectors. Full cycle validation is available to meet the specific regulatory needs of your facility. Benefits High Throughput: Supports busy CSSD and lab workflows with fast, efficient cycles Validated Disinfection: Meets global hygiene standards through thermal disinfection Flexible Programming: Customizable cycles for a wide range of cleaning applications Ergonomic & Safe: Easy loading, intuitive controls, and safe operation Long-Term Durability: Engineered for daily use in high-demand environments Conclusion Hnjdpfx Agjxhfm Aj Nju The Steris Reliance 380PG is a premium-grade washer/disinfector that sets the benchmark for performance, hygiene, and reliability in high-volume sterile processing. Whether in a hospital, laboratory, or pharmaceutical production facility, the 380PG delivers unmatched results with every cycle—backed by Steris’s legacy of innovation and support.

Condition: used, This listing is for the Lytzen ISO Class 5 (Class 100) Depyrogenation Oven . The unit is in full working condition and is ready for immediate use. Overview Lytzen Depyrogenation Ovens are high-performance dry heat sterilizers designed for sterilizing and depyrogenating pharmaceutical containers such as glass vials, ampoules, and bottles. These ovens maintain ISO Class 5 (Class 100) cleanroom conditions throughout the entire process cycle, even at elevated temperatures. Manufactured in Denmark, Lytzen ovens are recognized for their advanced chamber design, precision engineering, and full GMP compliance. Key Features ISO Class 5 at High Temperatures ISO 14644-1 Class 5 (Class 100) Certified: Maintains Class 5 air cleanliness throughout the entire cycle. Up to 280 °C Airflow Integrity: Delivers unidirectional HEPA-filtered airflow at temperatures up to 280 °C, enabled by Lytzen’s unique chamber construction and filter suspension system. Continuous Clean Air Protection: HEPA filtration remains stable and effective during heating, sterilizing, and cooling phases. Validated Depyrogenation & Sterilization Hnsdpfx Agoxhfmco Nju Dry Heat up to 280 °C: Validated for both sterilization and ≥3-log reduction of endotoxins. Exceptional Uniformity: Ensures reliable and consistent processing of glassware and components. High Load Capacity: Designed to support both small and large-scale pharmaceutical operations. Technical Specifications Cleanroom Classification: ISO 14644-1 Class 5 (Class 100) maintained throughout the cycle Operating Temperature: Up to 280 °C continuous operation Airflow Type: Unidirectional laminar airflow Filtration: HEPA H14 filters with advanced suspension system Chamber Material: AISI 316L stainless steel interior Controls: Siemens HMI interface Validation: GMP-compliant; supports IQ/OQ/PQ and CFR 21 Part 11 compliance Applications Pharmaceutical: Vial, ampoule, and glassware depyrogenation Biotech: Sterile preparation of components before aseptic fill Sterile manufacturing: Endotoxin removal for GMP environments Laboratory: Pilot-scale sterilization and dry heat validation Benefits True ISO Class 5 at 280 °C – unmatched cleanroom integrity during high-heat operation Regulatory Confidence – supports global GMP and FDA requirements Superior Engineering – long filter life and low maintenance through innovative construction Process Consistency – validated, repeatable depyrogenation cycles Scalable Solutions – available for lab, pilot, and full production use

Year of construction: 2002, condition: used, This listing is for the Ehret STE 1610/2/100 Sterilising Oven. The unit is in full working condition and is ready for immediate use. Overview The Ehret STE 1610/2/100 Sterilising Oven is a high-performance dry heat sterilizer designed for reliable and consistent sterilization of laboratory and pharmaceutical materials. Manufactured by Ehret, a trusted German brand in thermal processing equipment, the STE 1610/2/100 delivers precise temperature control and robust performance, making it ideal for applications requiring sterilization without moisture, such as glassware, metal instruments, and heat-stable laboratory components. Key Features Precise Dry Heat Sterilization High-Temperature Range: Operates up to 250 °C, suitable for complete sterilization and thermal decontamination. Uniform Temperature Distribution: Advanced air circulation ensures even heat distribution throughout the chamber. Validated Sterilization Cycles: Ideal for sterilizing glass, metal tools, and other heat-resistant materials with accuracy and repeatability. Robust Construction & Ergonomic Design Durable Stainless Steel Chamber: Corrosion-resistant and easy to clean, suitable for repeated sterilization cycles. User-Friendly Controls: Digital temperature controller with display for accurate setpoint adjustment and monitoring. Safety Features: Over-temperature protection, door interlock, and visual/audio alarms for enhanced operational safety. Technical Specifications Model: STE 1610/2/100 Temperature Range: Ambient +5 °C to 250 °C Chamber Volume: Approx. 100 litres Heating Method: Electrically heated with forced air circulation Temperature Control Accuracy: ±1 °C Construction: Stainless steel inner chamber; powder-coated steel exterior Control System: Digital PID controller with safety cut-off and time functions Power Supply: 230 V / 50–60 Hz (depending on configuration) Applications Pharmaceutical Laboratories: Dry sterilization of vials, stoppers, and instruments Medical Facilities: Sterilizing surgical tools, metal parts, and reusable components Research & Diagnostics: Sterilization of labware and experimental setups Industrial & QA Labs: Heat treatment, drying, and thermal conditioning of materials System Components Electrically heated drying/sterilization chamber Forced air circulation fan for uniform heating Hnjdpfexhflxex Ag Nou Digital control panel with setpoint and actual temperature display Safety thermostat with alarm system Removable shelving for flexible loading Quality Assurance All Ehret STE ovens are manufactured in compliance with DIN and ISO standards and undergo rigorous quality testing at the factory. Designed for reliable long-term use, the units support calibration, validation (IQ/OQ), and GMP documentation where required. Benefits Reliable Sterilization: Proven performance across thousands of cycles Accurate & Uniform Heating: Ensures consistent results and safe sterilization Low Maintenance: Durable components and easy-to-clean surfaces Safety-Compliant: Built with laboratory and industrial safety standards in mind Compact Footprint: Fits easily into lab or cleanroom environments Conclusion The Ehret STE 1610/2/100 Sterilising Oven is a dependable, precision-controlled dry heat sterilizer built for modern lab and pharmaceutical environments. Its combination of German engineering, validated performance, and operator-friendly design makes it a trusted solution for high-integrity sterilization processes.

Year of construction: 2002, condition: used, Lancer 1600 PCM Stainless Steel Washer Overview The Lancer Washer Infeed Type 1600 PCM DPSS is a superior pharmaceutical production washer designed to exceed all GMP requirements Ehret Technologies – Trio-Tech International. This industrial-grade washing system is specifically engineered for pharmaceutical and laboratory applications where stringent cleaning standards are essential. Key Features Designed to provide an adequate cleaning process using mechanical, thermal and chemical cleaning properties ETO Sterilizer - Fully Automatic ETO Sterilizer, Hospital Sterilizer Manufacturer Multi-level washing capabilities for maximum efficiency GMP (Good Manufacturing Practice) compliant design Pharmaceutical-grade construction and validation Chamber Specifications Internal chamber dimensions: 33 5/8"H × 27 3/4"D × 27 3/4"W ETO Sterilizer - Fully Automatic ETO Sterilizer, Hospital Sterilizer Manufacturer Large capacity design for high-volume processing Multiple rack positions for flexibility Construction & Materials 316L Stainless Steel Construction: Pharmaceutical-grade stainless steel throughout for corrosion resistance and easy sanitization cGMP Compliant: Meets current Good Manufacturing Practice requirements Robust Design: Built for continuous industrial use in demanding environments Control System Microprocessor-controlled operation Multiple programmable wash cycles Process monitoring and documentation capabilities Applications Pharmaceutical manufacturing equipment cleaning Laboratory glassware and instrument washing Medical device processing Research facility applications Biotechnology equipment cleaning Technical Specifications Model: 1600 PCM (Pharmaceutical Cleaning Module) Construction: 316L Stainless Steel Compliance: cGMP, FDA regulations Operation: Automated wash/rinse/dry cycles Chemical Integration: Automated detergent and rinse aid dosing Validation: IQ/OQ/PQ documentation available Hnodpfx Agsxhfkuo Nju Benefits Ensures consistent, validated cleaning results Reduces manual labour and contamination risk Meets strict pharmaceutical industry standards Large capacity increases throughput Automated operation improves efficiency and traceability This washer represents Lancer's commitment to providing pharmaceutical-grade cleaning solutions that meet the most demanding industry requirements for cleanliness, validation, and regulatory compliance.

Condition: used, This listing is for the CAS Biomat 2 Microbiological Safety Cabinet with Stand The unit is in full working condition and is ready for immediate use The BioMat 2 is a Class II microbiological safety cabinet—also known as a biosafety cabinet—designed to protect the user, the sample (or product), and the environment during handling of potentially hazardous or sterile biological materials Key Features & Capabilities Protection & Compliance Hjdpfxoxhfkbj Ag Nsnu Meets the European standard EN 12469:2000 for microbiological safety cabinets It shields both the operator and the product through an inward air curtain (front sash) and sterile downflow over the work surface. Aerosols and contaminants are filtered through HEPA filters before being exhausted or recirculated Construction & Safety Built with a 1.5 mm mild steel outer shell and 304 stainless steel interior. Side panels are made from 5 mm UV-resistant toughened glass Include safety alarms, airflow monitoring, and robust sealing under negative pressure to prevent leaks

Condition: used, This listing is for the Unity Scientific Spectra Star 2600XT bench‑top near‑infrared (NIR) analyzer The unit is in full working condition and is ready for immediate use The SpectraStar 2600XT‑is a high-performance, bench‑top near‑infrared (NIR) analyzer developed by Unity Scientific, designed for rapid, versatile compositional analysis across a wide variety of sample types, including solids, slurries, and liquids. Overview & Key Features Design & Functionality Dual Convection Technology: Offers adjustable fan speed from 0 % (natural convection) to 100 %, enabling tailored air circulation depending on the sample type or protocol Temperature Range: Operates from 5 °C above ambient up to 105 °C, making it suitable even for drying tasks Temperature Uniformity & Stability: With fan off: ±0.6 °C spatial uniformity With fan at full speed: ±0.2 °C to ±0.4 °C uniformity (at 37 °C) Temporal stability: ±0.1 °C (at 37 °C) Capacity & Build Interior Volume: 178 L (about 6.3 cubic feet) Hnodpfx Agjxhd I Ss Nou Shelving: Comes with 2 stainless-steel shelves (each supporting up to ~25 kg) and can accommodate up to 19 shelves for flexible arrangement Construction: Corrosion-resistant stainless steel interior (AISI 304) with easy-to-clean rounded corners Controls & Usability Controller: Microprocessor-based with a clear vacuum fluorescent display for easy setting of temperature, timers, and monitoring Timer Functionality: Programmable daily, weekly, or real-time ON/OFF cycles for scheduling experiments Extras: Internal power socket (120 V models) for operating devices like shakers or stirrers inside the chamber Internal glass viewing door and optional internal lighting for observing samples without opening the chamber RS‑232 interface for data logging and connectivity Stackable design without tools—efficient laboratory space use Safety & Maintenance Alarms: Automatic over- and under-temperature alert system protects sample integrity Security Model (IMH180‑S): Adds a lockable outer door and audible alarms for door‑open conditions Includes a certified 140 °C decontamination cycle (about six hours) to sterilize the chamber without needing an autoclave—ideal for high‑sterility environments Dimensions & Electrical Specs Feature Specification Exterior (W × D × H) 64 × 74 × 92 cm (25.2 × 29.1 × 36.2 in) Interior (W × D × H) ~46 × 54 × 70 cm (18.3 × 21.4 × 27.9 in) Weight ~70 kg (154 lb) Electrical (120 V) 1,020–1,390 W; 8.5 A at 60 Hz Materials Stainless steel (interior), durable housing Summary The Thermo Scientific Heratherm IMH180 is a high-performance, reliable incubator tailored for demanding laboratory tasks: Precision: Excellent temperature control and uniformity. Flexibility: Adjustable airflow, generous interior volume, and timer options. Convenience: Viewing window, internal socket, and connectivity via RS‑232. Cleanability & Space Efficiency: Stainless steel interior and stackable design. Advanced Safety (Security Model): Door alarms, lockable access, and high-temperature decontamination. Perfect for microbiology, cell culture, pharmaceutical testing, and drying applications where sample integrity and process control are critical.

Condition: used, This listing is for the Thermo Scientific Heratherm IMH180 Incubator The unit is in full working condition and is ready for immediate use The Thermo Scientific Heratherm IMH180 is a high-performance, reliable incubator tailored for demanding laboratory tasks: Precision: Excellent temperature control and uniformity. Flexibility: Adjustable airflow, generous interior volume, and timer options. Convenience: Viewing window, internal socket, and connectivity via RS‑232. Cleanability & Space Efficiency: Stainless steel interior and stackable design. Advanced Safety (Security Model): Door alarms, lockable access, and high-temperature decontamination. Perfect for microbiology, cell culture, pharmaceutical testing, and drying applications where sample integrity and process control are critical. Design & Functionality Dual Convection Technology: Offers adjustable fan speed from 0 % (natural convection) to 100 %, enabling tailored air circulation depending on the sample type or protocol Temperature Range: Operates from 5 °C above ambient up to 105 °C, making it suitable even for drying tasks Temperature Uniformity & Stability: With fan off: ±0.6 °C spatial uniformity With fan at full speed: ±0.2 °C to ±0.4 °C uniformity (at 37 °C) Temporal stability: ±0.1 °C (at 37 °C) Capacity & Build Interior Volume: 178 L (about 6.3 cubic feet) Shelving: Comes with 2 stainless-steel shelves (each supporting up to ~25 kg) and can accommodate up to 19 shelves for flexible arrangement Construction: Corrosion-resistant stainless steel interior (AISI 304) with easy-to-clean rounded corn Controls & Usability Controller: Microprocessor-based with a clear vacuum fluorescent display for easy setting of temperature, timers, and monitoring Timer Functionality: Programmable daily, weekly, or real-time ON/OFF cycles for scheduling experiments Extras: Internal power socket (120 V models) for operating devices like shakers or stirrers inside the chamber Internal glass viewing door and optional internal lighting for observing samples without opening the chamber RS‑232 interface for data logging and connectivity Stackable design without tools—efficient laboratory space use Safety & Maintenance Alarms: Automatic over- and under-temperature alert system protects sample integrity Hnodpsxhd Ixofx Ag Nou Security Model (IMH180‑S): Adds a lockable outer door and audible alarms for door‑open conditions Includes a certified 140 °C decontamination cycle (about six hours) to sterilize the chamber without needing an autoclave—ideal for high‑sterility environments Dimensions & Electrical Specs Feature Specification Exterior (W × D × H) 64 × 74 × 92 cm (25.2 × 29.1 × 36.2 in) Interior (W × D × H) ~46 × 54 × 70 cm (18.3 × 21.4 × 27.9 in) Weight ~70 kg (154 lb) Electrical (120 V) 1,020–1,390 W; 8.5 A at 60 Hz Materials Stainless steel (interior), durable housin

Condition: used, This listing is for 1 of 2 BWT LOOPO WFI Storage and Distribution System. The unit is in full working condition and is ready for immediate release. Overview This BWT LOOPO system is a high-performance Water for Injection (WFI) storage and distribution solution, designed for reliable and hygienic operation in pharmaceutical and biotech environments. Mounted on a robust stainless steel skid, the unit includes a high-grade stainless steel storage tank, engineered for ambient temperature WFI applications. The system features Siemens HMI controls for intuitive operation and precise system monitoring. Key Features - WFI Storage & Distribution at Ambient Temperature - 30 kW Power Capacity - Siemens HMI Touchscreen Interface - Fully skid-mounted for compact and efficient installation Hnsdpfx Agsxhdxwo Nsu - Stainless steel construction throughout – skid and tank - Ideal for pharmaceutical-grade applications - Designed for continuous circulation to prevent stagnation and microbial growth Technical Specifications - System Type: Ambient WFI Storage & Loop - Construction: Stainless Steel (Skid & Tank) - Control System: Siemens HMI - Power Supply: 30 kW - Installation Type: Skid-Mounted - Year of Manufacture: 2016 Applications - Pharmaceutical manufacturing - Biotech production facilities - Cleanroom and GMP environments - Laboratories requiring sterile WFI distribution

Condition: used, This listing is for the Amersham Pharma 35L BPG Cromatography Column The unit is in full working condition and is ready for immediate use BPG stands for Bio‑Process Glass or BioProcess Glass (sometimes called BPG columns). They are process‑scale chromatography columns used in biopharmaceutical / downstream protein purification. Hsdpfxoxhdw Ho Ag Nsnu Originally from Amersham / Pharmacia, now under GE Healthcare / Cytiva brands. Made to be hygienic, scalable, reproducible, for use in situations where high cleanliness, sterility, and regulatory compliance matter (e.g. GMP) A BPG column (short for BioProcess Glass column) is a process-scale chromatography column designed specifically for downstream purification in biopharmaceutical manufacturing — particularly for the purification of proteins, antibodies, and other biologics